Medicine For Lassa Fever

27112003 At hospital admission most patients have antibodies to the virus 53 with IgG and 67 with IgM4 Together enzyme linked immunosorbent assays ELISAs for Lassa virus antigen and for virus IgM are 88 sensitive and 90 specific for acute infection19 Other effects of illness include lymphocytopenia and a moderate thrombocytopenia which are maximal 10-11 days after. It is caused by infection with the Lassa virus a single-stranded RNA virus that belongs to the Arenaviridae family of viruses genus.

2016 Lassa Fever Epidemic

Treatment of Lassa Fever.

Medicine for lassa fever. Hospital ISTH Federal Medical Centre Owo and Federal Teaching Hospital Abakaliki FETHA. The median total direct medical cost for the treatment of La ssa fever was N80 70400. 41 Its use for prophylaxis of contacts with Lassa fever cases and for the treatment of other arenavirus infections has been proposed but no trial reports have been published to date.

The large Lassa fever outbreak in Nigeria between January and May 2018 increased our awareness of the need to have well-detailed and easily accessible guidelines for response. Lassa-convalescent plasma did not significantly reduce mortality in any of the high-risk groups. Early diagnosis of Lassa fever and treatment with ribavirin may prevent serious disease and death in the patient and can reduce the risk of transmission to unsuspecting contacts in the community.

01102020 Total and average direct medical cost of the treatment of Lassa fever. Treatment with ribavirin is 30 mgkg IV maximum 2 g loading dose followed by 16 mgkg IV maximum 1 gdose every 6 hours for 4 days then 8 mgkg IV maximum 500 mgdose every 8 hours for 6 days. Diagnostic proficiency and reporting of Lassa fever by physicians in Osun State of Nigeria.

21012020 Lassa fever is an illness caused by Lassa virus a single-stranded RNA hemorrhagic fever virus from the family Arenaviridae. It is an acute febrile viral illness lasting one to four weeks and it occurs in West Africa and some areas beyond. 31012019 Typically Lassa fever is diagnosed using enzyme-linked immunosorbent serologic assays ELISA.

These detect IgM and IgG antibodies and Lassa antigens. Facial edema as well as hemorrhage of gums nose and mouth may be observed in addition to severe nausea vomiting and chest back and abdominal pain. 27062018 Lassa fever is generally diagnosed by using enzyme-linked immunosorbent serologic assays ELISA.

The highest total direct medical cost. Most cases manifest as mild fever headache and malaise. Ribavirin has been evaluated for the treatment of severe Lassa fever cases and dramatically reduces the mortality rate provided it is given early in the illness.

The first of such is the Lassa Fever Diagnostic Laboratory Commissioned at Irrua Edo state in 2008. Treatment Ribavirin has been used with success in Lassa fever patients. Lassa fever is a viral haemorrhagic fever that spreads to humans through contact with infected rats.

26042021 Favipiravir has been proven safe in humans and effective for other illnesses such as the flu but its efficacy for treating Lassa fever is not yet known. 01012013 There is no vaccine for the prevention of Lassa fever though development is underway Adewuyi et al 2009Ehlkes et al 2017. Lassa Fever Treatment.

03062021 An acute zoonotic viral haemorrhagic fever endemic to West Africa. It has ultramodern diagnostic equipment donated and installed by the Harvard University Boston USA and Benerd-Nocht Institute of Tropical Medicine Hamburg Germany. One of the major challenges of treating Lassa fever is the nature of the disease.

Lassa Fever Isolation Ward also under construction in the same centre. In cases with abdominal pain in countries where Lassa is common Lassa fever is often misdiagnosed as appendicitis and intussusception which delays treatment with the antiviral ribavirin. MammarenavirusThe natural reservoir is the multimammate rat Mastomys natalensis a rodent found commonly in rural areas of tropical Africa that often colonises in or.

Ribavirin if begun within the first 6 days may reduce mortality up to 10-fold. In West Africa where Lassa is most common it is difficult to diagnose due to the absence of proper equipment to perform testing. We conclude that ribavirin is effective in the treatment of Lassa fever and that it should be used.

Olowookere SA et al. Olowookere SA Fatiregun AA Gbolahan OO Adepoju EG. In individuals with severe disease respiratory distress and shock may occur.

Medication Ribavirin Rebetol Copegus Ribasphere RibaPak Moderiba.

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